Neurotoxic Effects of Tetrahydroisoquinolines and Underlying Mechanisms
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چکیده
منابع مشابه
Neurotoxic Effects of Tetrahydroisoquinolines and Underlying Mechanisms
Tetrahydropapaveroline (THP), a neurotoxic tetrahydroisoquinoline alkaloid formed by condensation between dopamine and dopaldehyde, has been speculated to cause Parkinson's disease and also to contribute to alcohol dependence. Having two catechol moieties, THP may readily undergo oxidation to form an o-quinone intermediate with concomitant production of reactive oxygen species, which can cause ...
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ژورنال
عنوان ژورنال: Experimental Neurobiology
سال: 2010
ISSN: 1226-2560,2093-8144
DOI: 10.5607/en.2010.19.2.63